Now showing items 1-6 of 6

  • Airway responsiveness: role of inflammation, epithelium damage and smooth muscle tension 

    Gourgoulianis, K. I.; Domali, A.; Molyvdas, P. A. (1999)
    THE purpose of this study was the effect of epithelium damage on mechanical responses of airway smooth muscles under different resting tension. We performed acetylcholine (ACh) (10(-5) M)-induced contraction on tracheal ...
  • Clarithromycin reduces the severity of bronchial hyperresponsiveness in patients with asthma 

    Kostadima, E.; Tsiodras, S.; Alexopoulos, E. I.; Kaditis, A. G.; Mavrou, I.; Georgatou, N.; Papamichalopoulos, A. (2004)
    A randomised double-blind placebo-controlled study was designed to evaluate the effects of a semisynthetic macrolide antibiotic, clarithromycin, on bronchial hyperresponsiveness to methacholine in patients with a diagnosis ...
  • Epithelium-dependent regulation of airways smooth muscle function. A histamine nitric oxide pathway 

    Gourgoulianis, K.; Iliodromitis, Z.; Hatziefthimiou, A.; Molyvdas, P. A. (1998)
    THE airway epithelium is responsible for the production of a number of arachidonic acid and nonprostanoid inhibitory factors. Epithelium synthesises nitric oxide (NO) which may be important in regulating the function of ...
  • The influence of altitude in bronchial asthma 

    Gourgoulianis, K.; Brelas, N.; Hatziparasides, G.; Papayianni, M.; Molyvdas, P. A. (2001)
    Background. Some asthmatic children living in mountain areas experience significant improvement in daily symptoms and in the degree of bronchial obstruction. The aim of this study is to investigate the effect of altitude ...
  • Insulin NO-dependent action on airways smooth muscles 

    Papayianni, M.; Gourgoulianis, K. I.; Molyvdas, P. A. (2001)
    In order to find out how insulin acts on airway smooth muscle and which mechanisms could be involved, we studied the effect of insulin on contraction induced, first, by KCI and, second, by Acetylcholine (Ach), before and ...
  • Magnesium as a relaxing factor of airway smooth muscles 

    Gourgoulianis, K. I.; Chatziparasidis, G.; Chatziefthimiou, A.; Molyvdas, P. A. (2001)
    in the search for effective treatment of a life-threatening asthma attack, intravenous magnesium infusion has been studied in asthmatic patients because of its potential effect to reverse bronchospasm and improve pulmonary ...