Now showing items 1-14 of 14

  • Antimitochondrial antibodies of immunoglobulin G3 subclass are associated with a more severe disease course in primary biliary cirrhosis 

    Rigopoulou, E. I.; Davies, E. T.; Bogdanos, D. P.; Liaskos, C.; Mytilinaiou, M.; Koukoulis, G. K.; Dalekos, G. N.; Vergani, D. (2007)
    Background/Aims: Primary biliary cirrhosis (PBC) is characterised by the presence of immunoglobulin (Ig) G antimitochondrial antibodies (AMA), which are routinely detected by indirect immunofluorescence (IFL) using composite ...
  • A case of membranous nephropathy associated with Sjögren syndrome, polymyositis and autoimmune hepatitis 

    Stefanidis, I.; Giannopoulou, M.; Liakopoulos, V.; Dovas, S.; Karasavvidou, F.; Zachou, K.; Koukoulis, G. K.; Dalekos, G. N. (2008)
    Sjögren syndrome (SS) is a chronic systemic autoimmune disease characterized by lymphocytic infiltration of exocrine glands, especially lacrimal and salivary. The immunologic process which occurs in this syndrome is B cell ...
  • Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis 

    Liu, J. Z.; Hov, J. R.; Folseraas, T.; Ellinghaus, E.; Rushbrook, S. M.; Doncheva, N. T.; Andreassen, O. A.; Weersma, R. K.; Weismüller, T. J.; Eksteen, B.; Invernizzi, P.; Hirschfield, G. M.; Gotthardt, D. N.; Pares, A.; Ellinghaus, D.; Shah, T.; Juran, B. D.; Milkiewicz, P.; Rust, C.; Schramm, C.; Muler, T.; Srivastava, B.; Dalekos, G.; Nöthen, M. M.; Herms, S.; Winkelmann, J.; Mitrovic, M.; Braun, F.; Ponsioen, C. Y.; Croucher, P. J. P.; Sterneck, M.; Teufel, A.; Andrew, L. Mason; Saarela, J.; Leppa, V.; Dorfman, R.; Alvaro, D.; Floreani, A.; Onengut-Gumuscu, S.; Rich, S. S.; Thompson, W. K.; Schork, A. J.; Næss, S.; Thomsen, I.; Mayr, G.; König, I. R.; Hveem, K.; Cleynen, I.; Gutierrez-Achury, J.; Ricaño-Ponce, I.; Van Heel, D.; Björnsson, E.; Sandford, R. N.; Durie, P. R.; Melum, E.; Vatn, M. H.; Silverberg, M. S.; Duerr, R. H.; Padyukov, L.; Brand, S.; Sans, M.; Annese, V.; Achkar, J. P.; Boberg, K. M.; Marschall, H. U.; Chazouillères, O.; Bowlus, C. L.; Wijmenga, C.; Schrumpf, E.; Vermeire, S.; Albrecht, M.; Rioux, J. D.; Alexander, G.; Bergquist, A.; Cho, J.; Schreiber, S.; Manns, M. P.; Färkkilä, M.; Dale, A. M.; Chapman, R. W.; Konstantinos, N. Lazaridis; Franke, A.; Anderson, C. A.; Karlsen, T. H. (2013)
    Primary sclerosing cholangitis (PSC) is a severe liver disease of unknown etiology leading to fibrotic destruction of the bile ducts and ultimately to the need for liver transplantation. We compared 3,789 PSC cases of ...
  • Familial primary biliary cirrhosis: Like mother, like daughter? 

    Smyk, D. S.; Rigopoulou, E. I.; Pares, A.; Mytilinaiou, M. G.; Invernizzi, P.; Bogdanos, D. P. (2012)
    The reasons underlying why autoimmune diseases overwhelmingly affect women more than men are not clear. Nor are the reasons why autoimmune disease is more prevalent in families. This review uses primary biliary cirrhosis ...
  • Helicobacter pylori infection and respiratory diseases: A review 

    Roussos, A.; Philippou, N.; Gourgoulianis, K. I. (2003)
    In the past few years, a variety of extradigestive disorders, including cardiovascular, skin, rheumatic and liver diseases, have been associated with Helicobacter pylori (H. pylori) infection. The activation of inflammatory ...
  • The hygiene hypothesis and evolutionary medicine 

    Germenis, A. E. (2014)
    The hygiene hypothesis is an explanatory model for increases in the incidence of chronic inflammatory disorders which have become much more prevalent in developed countries during recent last decades. Accumulating evidence ...
  • Increased primary autoimmune thyroid diseases and thyroid antibodies in sarcoidosis: Evidence for an under-recognised extrathoracic involvement in sarcoido 

    Malli, F.; Bargiota, A.; Theodoridou, K.; Florou, Z.; Bardaka, F.; Koukoulis, G. N.; Gourgoulianis, K. I.; Daniil, Z. (2012)
    Objective and Design: Sarcoidosis has been associated with thyroid diseases. However, until today no definite conclusions have been drawn. We aimed to assess the frequency of thyroid disorders and the levels of thyroid ...
  • Infectomics and autoinfectomics: a tool to study infectious-induced autoimmunity 

    Bogdanos, D. P.; Smyk, D. S.; Rigopoulou, E. I.; Sakkas, L. I.; Shoenfeld, Y. (2015)
    The exposome represents all exogenous and endogenous environmental exposures that begin at preconception and carry on throughout life, while the microbiome reflects the microbial component of the exposome. We recently ...
  • Patterns of cognitive impairment in neurological disease 

    Markopoulou, K. (2010)
    Cognitive impairment is present in neurodegenerative disease, usually as part of a spectrum of symptoms that includes different domains of cognitive function. While the nature of the cognitive impairment tends to be ...
  • PBC Screen: An IgG/IgA dual isotype ELISA detecting multiple mitochondrial and nuclear autoantibodies specific for primary biliary cirrhosis 

    Liu, H.; Norman, G. L.; Shums, Z.; Worman, H. J.; Krawitt, E. L.; Bizzaro, N.; Vergani, D.; Bogdanos, D. P.; Dalekos, G. N.; Milkiewicz, P.; Czaja, A. J.; Heathcote, E. J.; Hirschfield, G. M.; Tan, E. M.; Miyachi, K.; Bignotto, M.; Battezzati, P. M.; Lleo, A.; Leung, P. S.; Podda, M.; Gershwin, M. E.; Invernizzi, P. (2010)
    A dual isotype (IgG, IgA) enzyme-linked immunosorbent assay (ELISA) designed to provide enhanced detection of primary biliary cirrhosis (PBC)-specific autoantibodies against both major mitochondrial and nuclear antigens ...
  • The risk of lymphoma development in autoimmune diseases: A meta-analysis 

    Zintzaras, E.; Voulgarelis, M.; Moutsopoulos, H. M. (2005)
    Background: The risk of development of non-Hodgkin lymphoma (NHL) in autoimmune patients has been investigated in several cohort studies. These studies revealed inconclusive results. To shed some light on this controversy, ...
  • Serum autoantibodies: From identification to clinical relevance 

    Invernizzi, P.; Bossuyt, X.; Bogdanos, D. P. (2013)
  • Severe unilateral corneal melting after uneventful phacoemulsification cataract surgery 

    Praidou, A.; Brazitikos, P.; Dastiridou, A.; Androudi, S. (2013)
    We present a rare case of severe unilateral corneal melt after uneventful phacoemulsification. A 38-year-old woman presented one week after uneventful phacoemulsification cataract surgery complaining of pain and blurred ...
  • T-Cell zeta chain expression, phosphorylation and degradation and their role in T-cell signal transduction and immune response regulation in health and disease 

    Eleftheriadis, T.; Antoniadi, G.; Liakopoulos, V.; Kortsaris, A. (2006)
    T-cell zeta chain expression, phosphorylation and degradation and their role in T-cell signal transduction and immune response regulation in health and disease. Zeta chain is a stable constituent of the antigen specific ...