Now showing items 1-7 of 7

  • Cytolytic T-cell response against Epstein-Barr virus in lung cancer patients and healthy subjects 

    Karanikas, V.; Zamanakou, M.; Soukou, F.; Kerenidi, T.; Tsougos, I.; Theodorou, K.; Georgoulias, P.; Gourgoulianis, K. I.; Germenis, A. E. (2010)
    Background: This study aimed to examine whether EBV seropositive patients with lung cancer have an altered virus-specific CTL response, as compared to age-matched healthy controls and whether any variation in this response ...
  • Foxp3 expression in human cancer cells 

    Karanikas, V.; Speletas, M.; Zamanakou, M.; Kalala, F.; Loules, G.; Kerenidi, T.; Barda, A. K.; Gourgoulianis, K. I.; Germenis, A. E. (2008)
    Objective: Transcription factor forkhead box protein 3 (Foxp3) specifically characterizes the thymically derived naturally occurring regulatory T cells (Tregs). Limited evidence indicates that it is also expressed, albeit ...
  • Indoleamine 2,3-dioxygenase (IDO) expression in lung cancer 

    Karanikas, V.; Zamanakou, M.; Kerenidi, T.; Dahabreh, J.; Hevas, A.; Nakou, M.; Gourgoulianis, K. I.; Germenis, A. E. (2007)
    Background: The expression of indoleamine 2,3-dioxygenase (IDO) by tumor cells has been considered as a major tumor immune escape mechanism. The aim of this study was to investigate the expression of IDO in lung cancer ...
  • Indoleamine 2,3-dioxygenose (IDO) expression in lung cancer 

    Karanikas, V.; Zamanakou, M.; Kerenid, T.; Dahabreh, J.; Hevas, A.; Nakou, M.; Gourgoulianis, K. I.; Germenis, A. E. (2007)
    Background: The expression of indoleamine 2,3-dioxygenase (IDO) by tumor cells has been considered as a major tumor immune escape mechanism. The aim of this study was to investigate the expression of IDO in lung cancer ...
  • Naturally occurring tumor-specific CD8(+) T-cell precursors in individuals with and without cancer 

    Karanikas, V.; Zamanakou, M.; Soukou, F.; Kerenidi, T.; Gourgoulianis, K. I.; Germenis, A. E. (2010)
    Boosting pre-existing, naturally occurring cytolytic CD8(+) T-cell (CTLs) responses directed against class-I MHC-restricted peptides of tumor antigens, represents a primary goal of cancer immunotherapy. The number of ...
  • Quantitative and qualitative assessment of anti-tumour specific T cells in patients with lung cancer and cancer free individuals 

    Karanikas, V.; Soukou, F.; Zamanakou, M.; Kalala, F.; Grammoustianou, E.; Kerenidi, T.; Gourgoulianis, K.; Germenis, A. (2008)
  • Tumor immune escape mediated by indoleamine 2,3-dioxygenase 

    Zamanakou, M.; Germenis, A. E.; Karanikas, V. (2007)
    Amongst the numerous mediators contributing towards the escape Of tumors from the host's immune response against them, the enzyme indoleamine 2,3-dioxygenase (lDO) has recently attracted special attention. By catabolizing ...