Now showing items 1-6 of 6

  • Combined prediction of Tat and Sec signal peptides with hidden Markov models 

    Bagos, P. G.; Nikolaou, E. P.; Liakopoulos, T. D.; Tsirigos, K. D. (2010)
    Motivation: Computational prediction of signal peptides is of great importance in computational biology. In addition to the general secretory pathway ( Sec), Bacteria, Archaea and chloroplasts possess another major pathway ...
  • Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat 

    Babbitt, P. C.; Bagos, P. G.; Bairoch, A.; Bateman, A.; Chatonnet, A.; Chen, M. J.; Craik, D. J.; Finn, R. D.; Gloriam, D.; Haft, D. H.; Henrissat, B.; Holliday, G. L.; Isberg, V.; Kaas, Q.; Landsman, D.; Lenfant, N.; Manning, G.; Nagano, N.; Srinivasan, N.; O'Donovan, C.; Pruitt, K. D.; Sowdhamini, R.; Rawlings, N. D.; Saier, M. H.; Sharman, J. L.; Spedding, M.; Tsirigos, K. D.; Vastermark, A.; Vriend, G. (2015)
    During 11-12 August 2014, a Protein Bioinformatics and Community Resources Retreat was held at the Wellcome Trust Genome Campus in Hinxton, UK. This meeting brought together the principal investigators of several specialized ...
  • CW-PRED: A HMM-based method for the classification of cell wall-anchored proteins of Gram-positive bacteria 

    Fimereli, D. K.; Tsirigos, K. D.; Litou, Z. I.; Liakopoulos, T. D.; Bagos, P. G.; Hamodrakas, S. J. (2012)
    Gram-positive bacteria have surface proteins that are often implicated in virulence. A group of extracellular proteins attached to the cell wall contains an LPXTG-like motif that is target for cleavage and covalent coupling ...
  • ExTopoDB: a database of experimentally derived topological models of transmembrane proteins 

    Tsaousis, G. N.; Tsirigos, K. D.; Andrianou, X. D.; Liakopoulos, T. D.; Bagos, P. G.; Hamodrakas, S. J. (2010)
    ExTopoDB is a publicly accessible database of experimentally derived topological models of transmembrane proteins. It contains information collected from studies in the literature that report the use of biochemical methods ...
  • Prediction of cell wall sorting signals in gram-positive bacteria with a hidden markov model: Application to complete genomes 

    Litou, Z. I.; Bagos, P. G.; Tsirigos, K. D.; Liakopoulos, T. D.; Hamodrakas, S. J. (2008)
    Surface proteins in Gram-positive bacteria are frequently implicated in virulence. We have focused on a group of extracellular cell wall-attached proteins (CWPs), containing an LPXTG motif for cleavage and covalent coupling ...
  • Prediction of signal peptides in archaea 

    Bagos, P. G.; Tsirigos, K. D.; Plessas, S. K.; Liakopoulos, T. D.; Hamodrakas, S. J. (2009)
    Computational prediction of signal peptides (SPs) and their cleavage sites is of great importance in computational biology; however, currently there is no available method capable of predicting reliably the SPs of archaea, ...