Now showing items 1-3 of 3

  • Early systemic sclerosis-opportunities for treatment 

    Sakkas, L. I.; Simopoulou, T.; Katsiari, C.; Bogdanos, D.; Chikanza, I. C. (2015)
    Systemic sclerosis (SSc) is characterized by microvasculopathy (Raynaud's phenomenon and fibrointimal proliferation), presence of autoantibodies and collagen deposition in skin (scleroderma) and internal organs. ...
  • Mechanisms of Disease: the role of immune cells in the pathogenesis of systemic sclerosis 

    Sakkas, L. I.; Chikanza, I. C.; Platsoucas, C. D. (2006)
    Systemic sclerosis is characterized by extensive fibrosis, microvascular stenosis and autoantibody production. All three characteristics can be accounted for by activation of cells of the immune system. Activation of T ...
  • New developments in the pathogenesis of systemic sclerosis 

    Sakkas, L. I. (2005)
    Systemic sclerosis (SSc) is characterized by extensive fibrosis, vasculopathy and activation of the immune system. Fibrosis can be caused by profibrotic cytokines, such as transforming growth factor-beta (TGF beta), ...