Now showing items 1-5 of 5

  • THE arcOGEN CONSORTIUM: STAGE 1 OF A GENOME-WIDE ASSOCIATION SCAN FOR OSTEOARTHRITIS 

    Panoutsopoulou, K.; Southam, L.; Rayner, W.; Zhai, G.; Beazley, C.; Arden, N.; Carr, A.; Chapman, K.; Deloukas, P.; Doherty, M.; McCaskie, A.; Olher, W.; Ralston, S.; Spector, T.; Valdes, A.; Wallis, G.; Wilkinson, M.; Arden, E.; Battley, K.; Blackburn, H.; Blanco, F.; Bumpstead, S.; Cupples, A.; Day-Williams, A.; Dixon, K.; Dohertys, S.; Elliott, K.; Evangelou, E.; Felson, D.; Gomez-Reino, J.; Gonzalez, A.; Gordon, A.; Gwilliam, R.; Hofman, A.; Hunt, S.; Ioannidis, J.; Jonsdottir, I.; Keen, R.; Kerkhof, H.; Kloppenburg, M.; Koller, N.; Lakenberg, N.; Lane, N.; Lee, A.; Meulenbelt, I.; Nevitt, M.; O'Neill, F.; Parimi, N.; Potter, S.; Rego-Perez, I.; Riancho, J.; Sherburn, K.; Slagboom, E.; Styrkarsdottir, U.; Sumillera, M.; Swift, D.; Tsezou, A.; Uitterlinden, A.; van Meurs, J.; Watkins, B.; Wheeler, M.; Mitchelle, S.; Zhu, Y.; Zmuda, J.; Zeggini, E.; Loughlin, J.; Arc, Ogen Consortium (2010)
  • Large-Scale Analysis of Association Between GDF5 and FRZB Variants and Osteoarthritis of the Hip, Knee, and Hand 

    Evangelou, E.; Chapman, K.; Meulenbelt, I.; Karassa, F. B.; Loughlin, J.; Carr, A.; Doherty, M.; Doherty, S.; Gomez-Reino, J. J.; Gonzalez, A.; Halldorsson, B. V.; Hauksson, V. B.; Hofman, A.; Hart, D. J.; Ikegawa, S.; Ingvarsson, T.; Jiang, Q.; Jonsdottir, I.; Jonsson, H.; Kerkhof, H. J. M.; Kloppenburg, M.; Lane, N. E.; Li, J.; Lories, R. J.; van Meurs, J. B. J.; Nakki, A.; Nevitt, M. C.; Rodriguez-Lopez, J.; Shi, D. Q.; Slagboom, E.; Stefansson, K.; Tsezou, A.; Wallis, G. A.; Watson, C. M.; Spector, T. D.; Uitterlinden, A. G.; Valdes, A. M.; Ioannidis, J. P. A. (2009)
    Objective. GDF5 and FRZB have been proposed as genetic loci conferring susceptibility to osteoarthritis (OA); however, the results of several studies investigating the association of OA with the rs143383 polymorphism of ...
  • Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility 

    Meulenbelt, I.; Bos, S. D.; Chapman, K.; van der Breggen, R.; Houwing-Duistermaat, J. J.; Kremer, D.; Kloppenburg, M.; Carr, A.; Tsezou, A.; Gonzalez, A.; Loughlin, J.; Slagboom, E. (2011)
    Objective To study whether common genetic variants of the genes involved in the complex regulatory mechanism determining the intracellular bio-availability of T3 influence osteoarthritis onset. Methods In total 17 genetic ...
  • RECOMMENDATIONS FOR STANDARDIZATION AND PHENOTYPE DEFINITIONS IN GENETIC STUDIES OF OSTEOARTHRITIS: THE TREAT-OA CONSORTIUM 

    Kerkhof, H. J.; Meulenbelt, I.; Arden, N.; Cooper, C.; Doherty, M.; Felson, D.; Gonzalez, A.; Ikegawa, S.; Jiang, Q.; Jonsdottir, I.; Kujala, U.; Lane, N.; Leino-Arjas, P.; Lohmander, S.; Luyten, F.; Nevitt, M.; Slagboom, E.; Spector, T.; Stefansson, K.; Tamm, A.; Tsezou, A.; Wilkinson, J.; Yoshimura, N.; Valdes, A.; van Meurs, J. (2010)
  • Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium 

    Kerkhof, H. J. M.; Meulenbelt, I.; Akune, T.; Arden, N. K.; Aromaa, A.; Bierma-Zeinstra, S. M. A.; Carr, A.; Cooper, C.; Dai, J.; Doherty, M.; Doherty, S. A.; Felson, D.; Gonzalez, A.; Gordon, A.; Harilainen, A.; Hart, D. J.; Hauksson, V. B.; Heliovaara, M.; Hofman, A.; Ikegawa, S.; Ingvarsson, T.; Jiang, Q.; Jonsson, H.; Jonsdottir, I.; Kawaguchi, H.; Kloppenburg, M.; Kujala, U. M.; Lane, N. E.; Leino-Arjas, P.; Lohmander, L. S.; Luyten, F. P.; Malizos, K. N.; Nakajima, M.; Nevitt, M. C.; Pols, H. A. P.; Rivadeneira, F.; Shi, D.; Slagboom, E.; Spector, T. D.; Stefansson, K.; Sudo, A.; Tamm, A.; Tamm, A. E.; Tsezou, A.; Uchida, A.; Uitterlinden, A. G.; Wilkinson, J. M.; Yoshimura, N.; Valdes, A. M.; van Meurs, J. B. J. (2011)
    Objective: To address the need for standardization of osteoarthritis (OA) phenotypes by examining the effect of heterogeneity among symptomatic (SOA) and radiographic osteoarthritis (ROA) phenotypes. Methods: Descriptions ...