Now showing items 1-8 of 8

  • Angiopoietin-2 associations with the underlying infection and sepsis severity 

    Lymperopoulou, K.; Velissaris, D.; Kotsaki, A.; Antypa, E.; Georgiadou, S.; Tsaganos, T.; Koulenti, D.; Paggalou, E.; Damoraki, G.; Karagiannidis, N.; Orfanos, S. E. (2015)
    Angiopoietin-2 (Ang-2) is an important mediator in sepsis. We have previously shown that endotoxemia levels are related to the underlying infection and affect septic patients' outcome. Based on this background we now ...
  • Bloodstream infections and sepsis in Greece: Over-time change of epidemiology and impact of de-escalation on final outcome 

    Koupetori, M.; Retsas, T.; Antonakos, N.; Vlachogiannis, G.; Perdios, I.; Nathanail, C.; Makaritsis, K.; Papadopoulos, A.; Sinapidis, D.; Giamarellos-Bourboulis, E. J.; Pneumatikos, I.; Gogos, C.; Armaganidis, A.; Paramythiotou, E. (2014)
    Background: Choice of empirically prescribed antimicrobials for sepsis management depends on epidemiological factors. The epidemiology of sepsis in Greece was studied in two large-periods.Methods: Sepsis due to bloodstream ...
  • The effect of homocysteine on the clinical outcomes of ventilated patients with severe sepsis 

    Tsantes, A.; Tsangaris, I.; Nikolopoulos, G.; Bagos, P.; Kopterides, P.; Antonakos, G.; Dimopoulou, I.; Vrioni, G.; Kapsimali, V.; Dima, K.; Armaganidis, A.; Travlou, A. (2010)
    Background. There is considerable evidence that elevated plasma homocysteine levels are associated with a prothrombotic milieu, whereas activation of the coagulation cascade is an important component of the pathogenesis ...
  • Genetic polymorphisms of innate and adaptive immunity as predictors of outcome in critically ill patients 

    Kompoti, M.; Michopoulos, A.; Michalia, M.; Clouva-Molyvdas, P. M.; Germenis, A. E.; Speletas, M. (2015)
    Sepsis and septic shock frequently cause the admission or complicate the clinical course of critically ill patients admitted in the intensive care units (ICU). Genetic variations disrupting the immune sensing of infectious ...
  • Open or Endovascular Repair of Aortoenteric Fistulas? A Multicentre Comparative Study 

    Kakkos, S. K.; Antoniadis, P. N.; Klonaris, C. N.; Papazoglou, K. O.; Giannoukas, A. D.; Matsagkas, M. I.; Kotsis, T.; Dervisis, K.; Gerasimidis, T.; Tsolakis, I. A.; Liapis, C. D. (2011)
    Objectives: To compare aortoenteric fistula (AEF) outcome after endovascular (EV-AEFR) or open repair (O-AEFR). Design: Multicentre retrospective comparative study. Materials/Methods: 25 patients with AEF (24 secondary, ...
  • Oxidative status in ICU patients with septic shock 

    Karapetsa, M.; Pitsika, M.; Goutzourelas, N.; Stagos, D.; Becker, A. T.; Zakynthinos, E. (2013)
    The aim of this pilot study was to investigate variability of oxidative stress during sepsis evolution. ICU patients with the diagnosis of septic shock were included. Thiobarbituric-acid reactive substances, total antioxidant ...
  • Statins in bacteremia, sepsis and pneumonia: Have we found the holy grail? 

    Stamatogiannis, N.; Makris, D.; Zakynthinos, E. (2009)
    Statins, beyond their lipid lowering properties, have pleiotropic properties that may modulate the inflammatory cascade and potentially could be useful in the management of inflammatory conditions such as bacteremia and ...
  • Toll-like receptors and their role in renal pathologies 

    Eleftheriadis, T.; Pissas, G.; Liakopoulos, V.; Stefanidis, I.; Lawson, B. R. (2012)
    Toll-like receptors (TLRs) are the first identified and best studied family of pattern recognition receptors. Expressed in immunocytes, TLRs initiate innate immune responses and concurrently shape the subsequent adaptive ...