Now showing items 1-20 of 32

  • Adipokines as mediators of endothelial function and atherosclerosis 

    Ntaios, G.; Gatselis, N. K.; Makaritsis, K.; Dalekos, G. N. (2013)
    For many decades, adipose tissue was considered as an inactive body compartment that was only used as an energy store. During the recent years, an increasing amount of data has revealed that adipose tissue is a major ...
  • Autoimmune hepatitis type 1 and primary biliary cirrhosis have distinct bone marrow cytokine production 

    Zachou, K.; Rigopoulou, E. I.; Tsikrikoni, A.; Alexandrakis, M. G.; Passam, F.; Kyriakou, D. S.; Stathakis, N. E.; Dalekos, G. N. (2005)
    We have recently reported differences in the hematopoiesis between autoimmune hepatitis type I (AIH-1) and primary biliary cirrhosis (PBC). In view of the notion that cytokines are regulators of hematopoiesis, we investigated ...
  • The Catabolic Role of Toll-Like Receptor 2 (TLR-2) Mediated by the NF-kappa B Pathway in Septic Arthritis 

    Papathanasiou, I.; Malizos, K. N.; Poultsides, L.; Karachalios, T.; Oikonomou, P.; Tsezou, A. (2011)
    Toll-like receptors (TLRs) are involved in mediating cell activation on stimulation with microbial components. Our objective was to investigate the role of 'PLR-2 mediated by the NF-kappa B pathway in septic arthritic ...
  • Comparison between clinical and ultrasonographic assessment in patients with erosive osteoarthritis of the hands 

    Koutroumpas, A. C.; Alexiou, I. S.; Vlychou, M.; Sakkas, L. I. (2010)
    The objective of this study is to assess the reliability of clinical examination in patients with erosive osteoarthritis (EOA). Eighteen patients with EOA underwent clinical examination for joint tenderness, bony swelling, ...
  • Drug-Induced Nephrotoxicity in Inflammatory Bowel Disease 

    Oikonomou, K. A.; Kapsoritakis, A. N.; Stefanidis, I.; Potamianos, S. P. (2011)
    Conservative management of inflammatory bowel disease (IBD) is based on a combination of drugs, including amino-salicylates (ASAs), steroids, antibiotics, immunosuppressives and biologic agents. Although various side effects ...
  • Enthesitis in psoriatic arthritis 

    Sakkas, L. I.; Alexiou, I.; Simopoulou, T.; Vlychou, M. (2013)
    Objectives: It is increasingly recognized that enthesitis in patients with psoriatic arthritis (PsA) is of clinical importance. We review data on the detection, assessment, and treatment of enthesitis and its related ...
  • Familial primary biliary cirrhosis: Like mother, like daughter? 

    Smyk, D. S.; Rigopoulou, E. I.; Pares, A.; Mytilinaiou, M. G.; Invernizzi, P.; Bogdanos, D. P. (2012)
    The reasons underlying why autoimmune diseases overwhelmingly affect women more than men are not clear. Nor are the reasons why autoimmune disease is more prevalent in families. This review uses primary biliary cirrhosis ...
  • Helicobacter pylori and autoimmune disease: Cause or bystander 

    Smyk, D. S.; Koutsoumpas, A. L.; Mytilinaiou, M. G.; Rigopoulou, E. I.; Sakkas, L. I.; Bogdanos, D. P. (2014)
    Helicobacter pylori (H. pylori) is the main cause of chronic gastritis and a major risk factor for gastric cancer. This pathogen has also been considered a potential trigger of gastric autoimmunity, and in particular of ...
  • Hemoglobin, erythropoietin and systemic inflammation in exacerbations of chronic obstructive pulmonary disease 

    Markoulaki, D.; Kostikas, K.; Papatheodorou, G.; Koutsokera, A.; Alchanatis, M.; Bakakos, P.; Gourgoulianis, K. I.; Roussos, C.; Koulouris, N. G.; Loukides, S. (2011)
    Background: Systemic inflammation may represent a possible cause of anemia. Previous data support that anemic patients with COPD present high erythropoietin (EPO) levels, suggestive of EPO resistance, possibly mediated ...
  • Heterogeneity testing in meta-analysis of genome searches 

    Zintzaras, E.; Ioannidis, J. P. A. (2005)
    Genome searches for identifying susceptibility loci for the same complex disease often give inconclusive or inconsistent results. Genome Search Meta-analysis (GSMA) is an established non-parametric method to identify genetic ...
  • High serum levels of HIF-1 alpha in psoriatic patients correlate with an over-expression of IL-6 

    Vasilopoulos, Y.; Sourli, F.; Zafiriou, E.; Klimi, E.; Ioannou, M.; Mamuris, Z.; Simos, G.; Koukoulis, G.; Roussaki-Schulze, A. (2013)
    Angiogenesis has been considered to be an important step in the initiation and progression of chronic diseases such as psoriasis. The hypoxia inducible factor 1 alpha (HIF-1 alpha), a critical hypoxia-induced factor that ...
  • Immunological mimic features of visceral leishmaniasis may systemic lupus erythematosus 

    Sakkas, L. I.; Boulbou, M.; Kyriakou, D.; Makri, I.; Sinani, C.; Germenis, A.; Stathakis, N. (2008)
    Objective: Visceral leishmaniasis (VL), caused by the intracellular parasite Leishmania, can present with fever, splenomegaly, pancytopenias, hypergammaglobulinemia, and autoantibody production. These features may mimic ...
  • Increased prevalence of anti-thyroid antibodies in patients with limited scleroderma 

    Danielides, S.; Mavragani, C. P.; Katsakoulas, I.; Zintzaras, E.; Drosos, A. A.; Vlachoyiannopoulos, P. G.; Moutsopoulos, H. M. (2011)
    Objectives: Thyroid dysfunction in the setting of systemic sclerosis (SSc) has been described previously. We aimed to determine the prevalence of anti-thyroid antibodies (ATA) in a large SSc cohort and to ascertain whether ...
  • Infectomics and autoinfectomics: a tool to study infectious-induced autoimmunity 

    Bogdanos, D. P.; Smyk, D. S.; Rigopoulou, E. I.; Sakkas, L. I.; Shoenfeld, Y. (2015)
    The exposome represents all exogenous and endogenous environmental exposures that begin at preconception and carry on throughout life, while the microbiome reflects the microbial component of the exposome. We recently ...
  • Interleukin-10G and interleukin-10R microsatellite polymorphisms and osteoarthritis of the knee 

    Fytili, P.; Giannatou, E.; Karachalios, T.; Malizos, K.; Tsezou, A. (2005)
    Objective To clarify and evaluate the possible role of interleukin-10G (IL-10G) and interleukin-10R (IL-10R) microsatellite polymorphisms of IL-10 gene in knee osteoarthritis (OA). Methods This was a case-control study. ...
  • Lectin-like oxidized low density lipoprotein receptor 1 (LOX-1) expression in human articular chondrocytes 

    Simopoulou, T.; Malizos, K. N.; Tsezou, A. (2007)
    Objective To investigate the involvement of oxidized low density lipoprotein (ox-LDL) and the expression of its receptor lectin-like oxidized low density lipoprotein receptor 1 (LOX-1) in osteoarthritis, by determining the ...
  • Lipid metabolism and osteoarthritis: Lessons from atherosclerosis 

    Gkretsi, V.; Simopoulou, T.; Tsezou, A. (2011)
    Osteoarthritis (OA) is an age-related degenerative disease comprising the main reason of handicap in the Western world. Interestingly, to date, there are neither available biomarkers for early diagnosis of the disease nor ...
  • Modeling of signaling pathways in chondrocytes based on phosphoproteomic and cytokine release data 

    Melas, I. N.; Chairakaki, A. D.; Chatzopoulou, E. I.; Messinis, D. E.; Katopodi, T.; Pliaka, V.; Samara, S.; Mitsos, A.; Dailiana, Z.; Kollia, P.; Alexopoulos, L. G. (2014)
    Objective: Chondrocyte signaling is widely identified as a key component in cartilage homeostasis. Dysregulations of the signaling processes in chondrocytes often result in degenerative diseases of the tissue. Traditionally, ...
  • Muscular Strength: Applications for Dancers 

    Koutedakis, Y.; Clarke, F.; Wyon, M.; Aways, D.; Owolabi, E. O. (2009)
    Muscle fibers can generally be divided into slow and fast twitch according to their contraction speed. Even though in individual normally has the same ratio of slow/fast muscle fibers throughout his or her body, the ...
  • Oxidative stress and inflammatory responses following an acute bout of isokinetic exercise in obese women with knee osteoarthritis 

    Germanou, E. I.; Chatzinikolaou, A.; Malliou, P.; Beneka, A.; Jamurtas, A. Z.; Bikos, C.; Tsoukas, D.; Theodorou, A.; Katrabasas, I.; Margonis, K.; Douroudos, I.; Gioftsidou, A.; Fatouros, I. G. (2013)
    Background: Obesity is associated with osteoarthritis and it is accompanied by chronic inflammation and elevated oxidative stress. Strengthening-type exercise is used in knee osteoarthritis (KOA) rehabilitation. This study ...