Now showing items 1-5 of 5

  • Alpha-actinin: A multidisciplinary protein with important role in B-cell driven autoimmunity 

    Kikonomou, K. G.; Zachou, K.; Dalekos, G. N. (2011)
    Alpha-actinin (α-actinin) is a ubiquitous cytoskeletal protein, which belongs to the superfamily of filamentous actin (F-actin) crosslinking proteins. It is present in multiple subcellular regions of both muscle and ...
  • A case of membranous nephropathy associated with Sjögren syndrome, polymyositis and autoimmune hepatitis 

    Stefanidis, I.; Giannopoulou, M.; Liakopoulos, V.; Dovas, S.; Karasavvidou, F.; Zachou, K.; Koukoulis, G. K.; Dalekos, G. N. (2008)
    Sjögren syndrome (SS) is a chronic systemic autoimmune disease characterized by lymphocytic infiltration of exocrine glands, especially lacrimal and salivary. The immunologic process which occurs in this syndrome is B cell ...
  • Deficiency of the B cell-activating factor receptor results in limited CD169+ macrophage function during viral infection 

    Xu, H. C.; Huang, J.; Khairnar, V.; Duhan, V.; Pandyra, A. A.; Grusdat, M.; Shinde, P.; McIlwain, D. R.; Maney, S. K.; Gommerman, J.; Löhning, M.; Ohashi, P. S.; Mak, T. W.; Pieper, K.; Sic, H.; Speletas, M.; Eibel, H.; Ware, C. F.; Tumanov, A. V.; Kruglov, A. A.; Nedospasov, S. A.; Häusinger, D.; Recher, M.; Lang, K. S.; Lang, P. A. (2015)
    The B cell-activating factor (BAFF) is critical for B cell development and humoral immunity in mice and humans. While the role of BAFF in B cells has been widely described, its role in innate immunity remains unknown. Using ...
  • Systemic sclerosis: From pathogenesis towards targeted immunotherapies 

    Sakkas, L. I.; Chikanza, I. C.; Platsoucas, C. D. (2012)
    Systemic sclerosis (SSc), a chronic disease with widespread collagen deposition, has three pathogenetic facets: immune activation, microvasculopathy and fibroblast activation. Immune activation and microvasculopathy occur ...
  • T-cells and B-cells in systemic sclerosis 

    Sakkas, L. I.; Platsoucas, C. D. (2010)
    Systemic sclerosis (SSc) is characterized by activation of fibroblasts with extensive deposition of collagen, by small vessel vasculopathy with fibrointimal proliferation, and activation of the immune system, with hyper-γ- ...