Now showing items 1-11 of 11

  • Characterization of novel intergenogroup and intergenotype recombinant noroviruses from central Greece 

    Ruether, I. G. A.; Dimitriou, T. G.; Tsakogiannis, D.; Kyriakopoulou, Z.; Amoutzias, G. D.; Gartzonika, C.; Levidiotou-Stefanou, S.; Markoulatos, P. (2014)
    Noroviruses (NoVs) are a major causative agent of acute gastroenteritis in humans. They are members of the Caliciviridae family and based on the genetic analysis of the RdRp and capsid regions, human NoVs are divided into ...
  • Chemoprevention of liver cancer by plant polyphenols 

    Stagos, D.; Amoutzias, G. D.; Matakos, A.; Spyrou, A.; Tsatsakis, A. M.; Kouretas, D. (2012)
    Primary liver cancer or hepatocellular carcinoma (HCC) is one of the most frequent tumors representing the fifth commonest malignancy worldwide and the third cause of mortality from cancer. Currently, the treatments for ...
  • Determination of human papillomavirus 16 physical status through E1/E6 and E2/E6 ratio analysis 

    Tsakogiannis, D.; Kyriakopoulou, Z.; Ruether, I. G. A.; Amoutzias, G. D.; Dimitriou, T. G.; Diamantidou, V.; Kotsovassilis, C.; Markoulatos, P. (2014)
    Human papillomavirus (HPV) 16 genome integration into the host chromosome is a crucial event during the life cycle of the virus and a major step towards carcinogenesis. The integration of HPV16 DNA promotes a constitutive ...
  • Evaluation and Properties of the Budding Yeast Phosphoproteome 

    Amoutzias, G. D.; He, Y.; Lilley, K. S.; Van de Peer, Y.; Oliver, S. G. (2012)
    We have assembled a reliable phosphoproteomic data set for budding yeast Saccharomyces cerevisiae and have investigated its properties. Twelve publicly available phosphoproteome data sets were triaged to obtain a subset ...
  • Evolution and taxonomic distribution of nonribosomal peptide and polyketide synthases 

    Amoutzias, G. D.; Van De Peer, Y.; Mossialos, D. (2008)
    The majority of nonribosomal peptide synthases and type I polyketide synthases are multimodular megasynthases of oligopeptide and polyketide secondary metabolites, respectively. Owing to their multimodular architecture, ...
  • Insights into the genetic diversity and evolution of Little cherry virus 1 

    Katsiani, A. T.; Maliogka, V. I.; Amoutzias, G. D.; Efthimiou, K. E.; Katis, N. I. (2015)
    Little cherry virus 1 (LChV-1), a member of the recently proposed genus Velarivirus, is a sweet cherry pathogen that has been recently reported to infect other Prunus species and is associated with various plant disorders. ...
  • Molecular epidemiology and evolutionary dynamics of Echovirus 3 serotype 

    Kyriakopoulou, Z.; Bletsa, M.; Tsakogiannis, D.; Dimitriou, T. G.; Amoutzias, G. D.; Gartzonika, C.; Levidiotou-Stefanou, S.; Markoulatos, P. (2015)
    Echovirus 3 (E3) serotype has been related with several neurologic diseases, although it constitutes one of the rarely isolated serotypes, with no report of epidemics in Europe. The aim of the present study was to provide ...
  • Posttranslational regulation impacts the fate of duplicated genes 

    Amoutzias, G. D.; He, Y.; Gordon, J.; Mossialos, D.; Oliver, S. G.; Van de Peer, Y. (2010)
    Gene and genome duplications create novel genetic material on which evolution can work and have therefore been recognized as a major source of innovation for many eukaryotic lineages. Following duplication, the most likely ...
  • Recombination among human non-polio enteroviruses: implications for epidemiology and evolution 

    Kyriakopoulou, Z.; Pliaka, V.; Amoutzias, G. D.; Markoulatos, P. (2015)
    Human enteroviruses (EV) belong to the Picornaviridae family and are among the most common viruses infecting humans. They consist of up to 100 immunologically and genetically distinct types: polioviruses, coxsackieviruses ...
  • Role of siderophores in cystic fibrosis pathogenesis: Foes or friends? 

    Mossialos, D.; Amoutzias, G. D. (2009)
    Cystic fibrosis (CF) is one of the most common genetic disorders among Caucasians. CF patients are susceptible to chronic lung infections caused by diverse microorganisms, therefore CF should be regarded as a polymicrobial ...
  • Siderophores in fluorescent pseudomonads: new tricks from an old dog 

    Mossialos, D.; Amoutzias, G. D. (2007)
    Iron is an essential nutrient for almost all bacteria; however, at neutral pH its bioavailability, is limited. Siderophores are iron-binding compounds of low molecular weight that enable the microorganisms that produce ...